The High Risk, High-Reward Research program, supported by Common Fund the at the National Institutes of Health has awarded 103 new research grants to support highly innovative scientists who propose visionary and broadly impactful meritorious behavioral and biomedical research projects.

Awards include the impact exposure to fracking might have on pregnancy and conception; how brain mechanisms influence memory performance; the neural basis of social bias and association using the female songbird as a model; tissue regeneration using the uterus as a model; a mixed methods examination of skin tone and health among African Americans across the United States; and a new model organism to lead in the development of an HIV vaccine.

The 103 awards total approximately $285 million in support from the institutes, centers, and offices across NIH over five years beginning in 2022, pending the availability of funds.