Dear Colleague,

We would like to inform you that the Patient-Centered Outcomes Research Institute (PCORI) plans to release the Phased Large Awards in Comparative Effectiveness Research (PLACER) PCORI Funding Announcement (PFA) as part of its 2023 funding Cycle 2 release on May 2, 2023.

The PLACER PFA seeks to fund high-quality, comparative clinical effectiveness research (CER) projects that will address critical decisional choices faced by patients, caregivers, clinicians, and stakeholders across the health and healthcare community. Investigators should propose an individual-level or cluster-randomized controlled trial of significant scale and scope for this PFA. The proposed trials should address critical decisional dilemmas that require important new evidence about the comparative clinical effectiveness of available interventions. Proposed studies should compare interventions that already have evidence of efficacy or are in widespread use. Clinical interventions (such as medications, diagnostic tests, or procedures) and delivery system interventions are appropriate for these studies.

We invite you to review the preannouncement on our website for more information about this PFA and register for the town hall on Friday, May 19, 2023 from 11:30 am -1:00 pm ET.

PCORI also plans to offer the PLACER PFA in Cycle 3 of 2023. More details regarding this release will be available at a future date.

Please feel free to share this information with anyone who may be interested.

Sincerely, 

Patient-Centered Outcomes Research Institute (PCORI)