To: School of Medicine Faculty

From: Jon M. Lindstrom, PhD, Chair - PSOM Limited Applications Selection Committee

Re: Identifying Senior Faculty for the Brain Research Foundation (BRF) - Scientific

Innovations Award (SIA)

https://thebrf.org/for-researchers/scientific-innovations-award-2/

Date: March 29, 2018

The Brain Research Foundation’s (BRF) Scientific Innovations Award (SIA) Program provides funding for innovative science in both basic and clinical neuroscience. This funding mechanism is designed to support creative, exploratory, cutting edge research in well-established laboratories, under the direction of senior investigators. (See attachment for complete guidelines.)

The BRF has invited the University to nominate one senior (tenured) faculty member to submit a SIA Letter of Intent (LOI). A committee established by the Office of the Vice Provost for Research (OVPR) will determine the final candidate who will represent the University. The PSOM Limited Applications Committee will review internal proposals and forward their nomination to OVPR for final determination.

Eligibility:

• A full-time tenured professor or associate professor, working in the area of studies of brain function in health and disease.
• Current major NIH or other peer-reviewed funding is preferred but evidence of such funding in the past three years is essential.
• Studies should be related to either normal human brain development or specifically identified disease states. This includes molecular and clinical neuroscience as well as studies of neural, sensory, motor, cognitive, behavioral and emotional functioning in health and disease.
• The grant proposal must detail a new research project that is not funded by other sources.
• The grant is not to be used as a source of bridge funding.

Ineligibility:

• PI is ineligible if they are an assistant professor or professor emeritus.
• PI is ineligible if they are a research associate professor or research professor.
• PI is ineligible to submit more than one BRF SIA proposal in a funding period.
• PI is ineligible if they have BRF funding that will overlap this grant period.
• PI is ineligible if they have been awarded prior BRF funding, but have failed to submit scientific and financial reports at the end of their grant period.
• PI is ineligible if they are a member of the BRF Scientific Review Committee.
• PI is ineligible if they are a relative of BRF a representative, including the SRC, as defined by the Foundation.

Objectives:

• The objective of the SIA is to support projects that may be too innovative and speculative for traditional funding sources but still have a high likelihood of producing important findings.
• It is expected that investigations supported by these grants will yield high impact findings and result in major grant applications and significant publications in high impact journals.
• This should be a unique project for senior investigators who are encouraged to stretch their imagination into areas that can substantially change an area of research.

Funding and Award Period:

The total award is limited to $150,000 (direct costs) for a two-year grant period. Based on the quality of applications, the BRF anticipates funding a total of $450,000 in grants.

PSOM Limited Applications Committee LOI Submission Guidelines:

Each nominee must submit a proposal that includes the following:

• A letter of nomination from his or her Department Chair or Division Chief
• Research Proposal (no longer than 2 pages and must include a title) that describes the rationale, approach and timeline for completion. Include a section describing why the proposal is too innovative and speculative for traditional funding sources but still has a high likelihood of producing important findings. References are not included in the two page limit. Please use 1 inch margin and size 12 font.
• Biographical sketch (using current NIH format) with other support page (5 page maximum). Note: As per guidelines: Current major NIH or other peer-reviewed funding is preferred but evidence of such funding in the past three years is essential.

Materials must be submitted as a single pdf in the following order: nomination letter, research proposal, references, and biosketch. The subject line should read: SIA_Candidate’s Surname_Candidate’s first name e.g. SIA_Smith_Jane.

Proposals must be submitted by 9:00 AM, Thursday, May 3, 2018 to Connie Weinstein at clw@pennmedicine.upenn.edu. If you have any questions, Connie can also be reached at 215-898-0132.